Reference · GLP-1 / incretin

Semaglutide

GLP-1 receptor agonist. Slows gastric emptying, modulates insulin response, and reduces appetite.

Not medical advice. The ranges below record what people log, not what anyone should take. FDA-approved compounds have separate prescribed dosing on-label.
Molecular weight
4,113.6 Da
Half-life
~7 days
Cadence people log
weekly SC
Range people log
0.25–2.4 mg / wk
Class
GLP-1 / incretin
Regulatory status
FDA-approved

FDA-approved as Ozempic (T2D), Wegovy (weight management), Rybelsus (oral T2D). Off-label use is outside the approved label.

Reconstituting Semaglutide

The calculator takes vial mass, BAC water volume and your target dose, and returns the exact draw on a U-40, U-50 or U-100 insulin syringe. It does the arithmetic; it does not suggest what the dose should be.

Open the reconstitution calculator →

Others in GLP-1 / incretin

TirzepatideRetatrutide
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pepme.health · 2026 · US, 18+not medical advice · descriptive, not prescriptive